Multi–step Organic Synthesis – A Guide Through Experiments

Description

By (author) Bogliotti, N

Short /annotation
Combining theoretical knowledge, practical considerations as well as structural elucidation, this textbook presents 16 independent exercises based on published research articles to inspire students by way of having to solve real-life problems in chemistry.


Combining theoretical knowledge of synthetic transformations, practical considerations, structural elucidation by interpretation of spectroscopic data as well as rationalization of structure-property relations, this textbook presents a series of 16 independent exercises, including detailed s of experimental procedures, questions, and answers. The experimental s are very helpful for guiding less experienced students towards a better understanding of practical aspects in synthetic organic chemistry, while the broad scope of the questions and answers is excellent for learning purposes. The exercises are based on published research articles, adapted for didactic purposes, and will thus inspire students by way of having to solve real-life problems in chemistry. A must-have for MSc and PhD students as well as postdocs in organic chemistry and related disciplines, and lecturers and organizers of lab courses in organic chemistry.

Table of contents
Foreword1) Atovaquone: An Antipneumocystic Agent2) SEN794: A SMO Receptor Antagonist3) Synthesis of a H1-H3 Antagonist4) Synthesis of Eletriptan5) Total Synthesis and Structure Revision of Streptophenazine A6) Synthesis of Leiodermatolide: A Biologically Active Macrolide7) Total Synthesis of Stemoamide8) Total Synthesis and Structure Revision of Caraphenol B9) Synthetic Routes Towards Muricatacin and Analogues10) Asymmetric Synthesis of (-)-Martinellic Acid

Biographical note
Nicolas Bogliotti is Assistant Professor at Ecole normale superieure Paris-Saclay, France. After his undergraduate studies at Universite Nice Sophia-Antipolis, France, he obtained his MSc and PhD Degrees at Universite Pierre et Marie Curie in Paris, France. He was a postdoc at ETH Zurich, Switzerland and Institut Curie, France, before his current position. His research interests focus on the synthesis of photosensitive molecules allowing visualization of recognition events, induction of a biological response and modulation of chemical reactivity.Roba Moumne is Assistant Professor at Universite Pierre et Marie Curie, France. She studied chemistry and completed her MSc and PhD at the same university. Before her current position, she was also a postdoctoral fellow at Max-Planck-Institut in Mulheim and der Ruhr, Germany, at University of Zurich, Switzerland and at Universite Paris Descartes, France. Her research interests include bioorganic chemistry and peptide synthesis.

Flap / cover copy
Combining theoretical knowledge of synthetic transformations, practical considerations, structural elucidation by interpretation of spectroscopic data as well as rationalization of structure-property relations, this textbook presents a series of 16 independent exercises, including detailed comments, questions, and answers.The comments are very helpful for guiding less experienced students toward a successful approach to problem-solving, while the broad scope of the questions and answers is excellent for learning purposes. The exercises are based on published research articles, adapted for didactic purposes, and will thus inspire students by way of having to solve real-life problems in chemistry.
A must-have for MSc and PhD students as well as postdocs in organic chemistry and related disciplines, and lecturers and organizers of lab courses in organic chemistry.